TMBRA - Rider Board

 
 FAQFAQ   SearchSearch   MemberlistMemberlist   UsergroupsUsergroups   RegisterRegister 
 ProfileProfile   Log in to check your private messagesLog in to check your private messages   Log inLog in 

Links

 
Post new topic   Reply to topic    TMBRA - Rider Board Forum Index -> Ask the Bike Doc
View previous topic :: View next topic  
Author Message
Anonymous
Guest





PostPosted: Mon Jun 02, 2008 8:46 am GMT +0000    Post subject: Links Reply with quote

Hi Doc! A year or so ago, you posted links to some studies that indicate ibuprofen is not as good for recovery as a hot bath and a massage. It seems that the ibuprofen restricts the release of prostigens which does not allow blood flow like a massage does. Can you provide those links again, please? The hard drive on my computer died and took those links with it.

Thanks!
Back to top
The Bike Doc
250+


Joined: 08 May 2003
Posts: 1369
Location: Corpus Christi and Warda, Texas

PostPosted: Fri Jun 06, 2008 9:58 pm GMT +0000    Post subject: Reply with quote

DC:

Here is the link to that original post:

http://tmbra.org/board/viewtopic.php?t=4900

You can also go to www.pubmed.gov and do your own search using search terms of: NSAID AND blood vessels AND exercise

Thanks,
_________________
Paul K. Nolan, MD
AKA: The Bike Doc
Back to top
View user's profile Send private message Visit poster's website
The Bike Doc
250+


Joined: 08 May 2003
Posts: 1369
Location: Corpus Christi and Warda, Texas

PostPosted: Mon Jun 16, 2008 6:24 am GMT +0000    Post subject: Reply with quote

DC:

Here is the posting again. The TMBRA Forum is being purged of older posts so I copied and pasted the prior posting here for reference.

Nonsteroid anti-inflamatory drugs (NSAID) , of which Motrin belongs, have been shown to constrict blood vessels. This can lead to reduce blood flow to exercising muscles. Further NSAID can inhibit the formation of new blood vessels. New blood vessels to the muscles are formed by regular training and exercising which improves endurance. Yet the very medication taken for aches and pains, NSAID and acetaminophen (Tylenol) inhibit this desired effect. Additionally, while there are therapeutic levels in the blood of the NSAID the platelets are inhibited and a crash can lead to much bigger bruising and bleeding from cuts. Aspirin is unique in that the platelet inhibiting nature lasts one week not just several hours as is the case with Motrin and the other NSAID. For those who must take a daily aspirin to prevent blood clots they should not stop taking the asprin, the benefits then out weigh the risks.

Ibuprofen (Motrin) and acetaminophen (Tylenol) have been shown to impair muscle protein synthesis after exercise and to reduce the release of the prostaglandins that are associated with blood vessel dialation and growth. Exercise triggers the changes that lead to muscle growth and to inhibit the desirable muscle protien synthesis with medications taken after exercise is counter productive to the goals of training. I have provide links to three articles that discuss some of these issues. There are many more available if you want to do a PubMed search for them.

http://ajpendo.physiology.org/cgi/reprint/282/3/E551

http://jcem.endojournals.org/cgi/reprint/86/10/5067

http://jap.physiology.org/cgi/reprint/86/2/598

My recommendations to prevent the aches and pains of training and racing is to progressively train, increasing your intensity noi more than 10% each week and avoiding going too hard too soon to avoid percipitating an overuse injury. Additionally, daily stretching exercises should be incorperated help keep the muscles and joints limber and less prone to incuring injuries. Get the excellent book, Stretching by Bob and Jean Anderson. It is a valuable resource in teaching you the correct way to stretch.

If you must take something for aches after an event, try icing and massaging for the first couple days then switch to warm soaks and massaging for the next several days afterward. If you feel you must take a medication to relive the pain afterwards, acetaminophen probably has the lesser of the undesirable side effects on the muscle. However, if someone drinks more than two drinks (beer, wine, &/or liqour) a day even standard dose acetaminophen can be toxic to the liver.

It was good question you asked and hopefully, I have not overwhelmed you with too much information, but instead, provided you with the rational for what some might think is unusual recommendations in light of the heavy marketing of the medications in question.

Thanks,
_________________
Paul K. Nolan, MD
AKA: The Bike Doc
Back to top
View user's profile Send private message Visit poster's website
Display posts from previous:   
Post new topic   Reply to topic    TMBRA - Rider Board Forum Index -> Ask the Bike Doc All times are GMT - 6 Hours
Page 1 of 1

 
Jump to:  
You cannot post new topics in this forum
You cannot reply to topics in this forum
You cannot edit your posts in this forum
You cannot delete your posts in this forum
You cannot vote in polls in this forum


Powered by phpBB © 2001, 2005 phpBB Group